A printing specification method and printing specification device for specifying a spot color, which differs from process colors, as a substitution color, when setting the substitution color for a color plate of one of the process colors and performing printing processing. The printing specification method includes extracting spot colors from a spot color database, displaying a list of names of the extracted spot colors, and specifying a spot color corresponding to a name that has been selected from the list as the substitution color. The spot color database is based on color information which includes characteristic values, which specify the spot colors, and spot color names. The extraction is performed on the basis of a characteristic value which sets a reference point and of a tolerance range of this characteristic value.