Patent 7422861 was granted and assigned to Novartis on September, 2008 by the United States Patent and Trademark Office.
Different-sequence peptoids, including lipid- and sterol-conjugated peptoids, are found to be effective in transfection of cells with oligonucleotides. Combinatorial libraries of such peptoids can be screened efficiently in a high-throughput format, and selected peptoids are identified post-screening.