Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
September 9, 2008
Patent Application Number
10451291
Date Filed
December 21, 2001
Patent Primary Examiner
Patent abstract
Dislosed is the integrin-binding domain of MAP kinase. Interaction between MAP kinase and integrin via this domain activates MAP kinase and initiates cellular activity. Methods of modulating cellular activity by inhibiting direct MAP kinase-integrin binding are provided. These methods have particular use in inhibiting growth of cancer cells.
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