Patent 7423121 was granted and assigned to Neurosearch A/S on September, 2008 by the United States Patent and Trademark Office.
The present invention relates to a novel voltage gated sodium channel located in the brain, nucleotides coding for it, vectors and host cells containing the same, transgenic non-human animal capable of expressing the sodium channel, and methods of screening for modulators of the channel such as modulators for use in the treatment of seizures, and conditions related to the limbic system and limbic regions including limbic seizures.