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US Patent 7429667 Phenylamino isothiazole carboxamidines as MEK inhibitors

Patent 7429667 was granted and assigned to Ardea Biosciences, Inc. on September, 2008 by the United States Patent and Trademark Office.

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Patent abstract

The invention concerns compounds which inhibit MEK and which have activity as anti-neoplastic agents. These compounds include N-substituted-3-hydroxy-5-arylamino-isothiazole-4-carboxamidines. Also included are the tautomeric isothiazol-3(2H)-ones.

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