Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 21, 2008
Patent Application Number
10991079
Date Filed
November 16, 2004
Patent Citations Received
0
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Patent Primary Examiner
Patent abstract
The present invention provides for an improved in vitro tissue assembly system and related methods that includes and uses a bioreactor, a porous mandrel disposed in the bioreactor, and components that provide for the circulation of culture media and cell suspensions within the bioreactor and through the porous mandrel. The circulation of the culture media and cell suspensions within the bioreactor produces a radial, convective flow and drag forces that result in the deposition of cells on the mandrel to form a tissue construct. Upon completion of the culture and tissue formation process, the tissue construct may be removed from the mandrel for subsequent in vivo use.
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