Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hideto Ohno0
Koichi Ishiguro0
Masaki Imagawa0
Date of Patent
October 28, 2008
Patent Application Number
11055747
Date Filed
February 11, 2005
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides an antibody which specifically recognizes a CNS tau protein but not a peripheral tau protein. More specifically, the present invention provides an antibody obtainable by using a polypeptide comprising an amino acid sequence of a connective portion between the amino acid sequence encoded by Exon 4 of a gene encoding a tau protein and the amino acid sequence encoded by Exon 5 thereof as an epitope specific to the isoform of tau protein predominantly existing in central nervous tissues. The present invention further provides a method of detecting Alzheimer's disease and a reagent kit using the antibody.
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