Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
William C. Fanslow, III0
James F. Smothers0
Revital Kariv0
Date of Patent
November 11, 2008
0Patent Application Number
111123040
Date Filed
April 22, 2005
0Patent Primary Examiner
Patent abstract
Anti-CD148 antibodies and antigen-binding regions thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding regions, are described. Also described are methods of using such antibodies and antigen-binding regions to bind CD148 epitopes and activate CD148 function, such as inhibition of angiogenesis. Epitopes that can be used to activate CD148 function and anti-angiogenesis activity are also described, as well as methods of identifying compounds that can bind them.
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