Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Rohn Lee Millican, Jr.0
Wolfgang Glaesner0
Andrew Mark Vick0
Date of Patent
November 18, 2008
0Patent Application Number
105586270
Date Filed
June 10, 2004
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides specific GLP-1 analogs fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, decreased immunogenicity, and reduce effector activity. The fusion proteins are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that would be benefited by lowering plasma glucose, inhibiting gastric and/or intestinal motility and inhibiting gastric and/or intestinal emptying, or inhibiting food intake.
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