A DC-DC converter capable of operating in a pulse-skipping mode for transforming power provided by a power generator for a load circuit includes a driving circuit for generating a gate driving signal according to a feedback signal and a pulse-skipping-mode control signal, a converter circuit for transforming power provided by the power generator for the load circuit according to the gate driving signal, a feedback circuit for generating the feedback signal for the driving circuit according to a feedback voltage of the load circuit, and a pulse-skipping-mode control circuit for generating the pulse-skipping-mode control signal and adjusting on-time of the generated pulse-skipping-mode control signal according to voltages outputted from the power generator and the converter circuit, so as to adjust voltage outputted from the converter circuit via the driving circuit.