Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Wayne M. Barnes0
Date of Patent
December 16, 2008
Patent Application Number
08483535
Date Filed
June 7, 1995
Patent Primary Examiner
Patent abstract
A formulation of thermostable or other DNA polymerases comprising (a) at least one thermostable or other DNA polymerase which lacks 3′-exonuclease activity, and (b) at least one thermostable DNA polymerase exhibiting 3′-exonuclease activity, wherein the ratio of (a) to (b) is greater than 1 to 1. Also provided is an improved method for enzymatic extension of DNA strands, especially while, but not limited to, amplifying nucleic acid sequences by polymerase chain reaction wherein the above formulation is made and used to catalyze primer extension, are also provided.
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