An electrostatic discharge (“ESD”) protection device, which includes a thyristor circuit, in the ESD case increases a resistance of the ESD protection device in comparison with a non-ESD case, by means of a switch. An ESD protection arrangement may include a ESD protection device to protects circuits with multiple voltage potentials. An ESD protection system may also include an ESD protection arrangement, to which an ESD signal is fed via a bus of the ESD protection system. The ESD protection device and ESD protection arrangement, and thus the ESD protection system, can be provided in a compact semiconductor arrangement.