Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
January 20, 2009
Patent Application Number
09914046
Date Filed
February 22, 2000
Patent Citations Received
Patent Primary Examiner
Patent abstract
Nucleic acid-immunoliposome compositions useful as therapeutic agents are disclosed. These compositions preferably comprise (i) cationic liposomes, (ii) a single chain antibody fragment which binds to a transferrin receptor, and (iii) a nucleic acid encoding a wild type p53. These compositions target cells which express transferrin receptors, e.g., cancer cells. These compositions can be used therapeutically to treat persons or animals who have cancer, e.g., head and neck cancer, breast cancer or prostate cancer.
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