Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Fiorenzo Stirpe0
Andrea Bolognesi0
Date of Patent
January 20, 2009
0Patent Application Number
107589020
Date Filed
January 16, 2004
0Patent Primary Examiner
Patent abstract
The invention relates to a novel ribosome-binding protein derived from Bougainvillea spectabilis having a molecular weight of about 26,000 daltons by polyacrylamide gel electrophoresis under reducing and non-reducing conditions, a pI of about 9.0, and a specified amino-terminal amino acid sequence. The invention further relates to a conjugate of the protein with a targeting ligand, such as an antibody, to form an immunotoxin. The protein and the conjugate are useful in therapy, for example, in the control of tumour cells or viruses.
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