Patent 7482455 was granted and assigned to Smithkline Beecham Limited on January, 2009 by the United States Patent and Trademark Office.
3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.