Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Rudi Hrncic0
Alan Solomon0
Jonathan Stuart Wall0
Maria Schell0
Date of Patent
February 3, 2009
Patent Application Number
09825872
Date Filed
April 5, 2001
Patent Primary Examiner
Patent abstract
The present invention provides a therapeutic method for removing amyloid fibrils from a patient. The present invention also provides a transgenic animal that develops systemic AA amyloidosis within three weeks for use as a tool to investigate AA amyloidosis and to evaluate agents that may be potentially useful in preventing and treating amyloid-related disorders. Further, the present invention provides diagnostic assays for monitoring immunoglobulin light chain fibrillogenesis in real-time and for identification of the chemical nature of the protein in amyloid deposits which enables the determination of the type of amyloidosis for therapeutic and prognostic purposes.
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