A perfume spray head structure generally comprises a main body, a spray nozzle, a gas guide device, and a gas supply tube, wherein the spray nozzle, the gas guide device, and the gas supply tube are pre-assembled together and then coupled with the main body. By the use of the pre-assembled structure, the assembly process can be performed conveniently and the occurrence of displacement can be avoided. In addition, the spray head has gaps formed thereon for passage of gas and perfume liquid. The perfume liquid is sprayed out via the gaps so as to form uniform perfume mists. The perfume spray head structure of the present invention can avoid the occurrence of non-uniform spray mists, which is caused by the displacement of the spray channel.