Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Steven Geysens0
Roland Contreras0
Date of Patent
February 17, 2009
Patent Application Number
11225804
Date Filed
September 12, 2005
Patent Primary Examiner
Patent abstract
The present invention relates to the use of a glucosidase II mutation to increase protein secretion in eukaryotic cells. The present invention relates further to the use of eukaryotic cells, comprising a mutant glucosidase II gene, possibly in combination with the expression of a recombinant α-1,2-mannosidase gene and/or a recombinant N-acetylglucosaminyl-transferase gene, as a host for protein secretion.
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