Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
February 17, 2009
Patent Application Number
11291668
Date Filed
December 1, 2005
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to the production of a transgenic bovine which comprises a genetic modification that results in inactivation and loss of expression of its endogenous antibodies, and the expression of xenogenous antibodies, preferably human antibodies. This is effected by inactivation of the IgM heavy chain expression and, optionally, by inactivation of the Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of non-bovine antibodies, preferably human antibodies.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
