An anti-tamper system is provided. The anti-tamper system comprises a clamshell protective encasement adapted to encapsulate at least one device on a single circuit board such that at least one electrical connector of the single circuit board is accessible. The anti-tamper system also comprises one or more sensors embedded inside the clamshell protective encasement, the one or more sensors being adapted to detect unauthorized attempts to tamper with the clamshell protective encasement.