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US Patent 7498140 Direct detection of biomolecules in a gel

Patent 7498140 was granted and assigned to Pierce Biotechnology on March, 2009 by the United States Patent and Trademark Office.

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Patent abstract

A method for detecting a target biomolecule directly in a polyacrylamide gel in which it has been separated from other substances. Prior to binding the target to a probe and while the target biomolecule remains in the gel, the gel is immersed in a water miscible aqueous extracting medium containing a base to shrink the gel by at least about ten percent, and then the gel is washed with water to restore the gel to substantially its original size.

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