Patent 7501518 was granted and assigned to Genzyme on March, 2009 by the United States Patent and Trademark Office.
Methods for preparing 2,6-diaryl piperidine derivatives are described. More particularly, 2,6-diaryl piperidines having formula 1-4 are prepared by cyclocondensation of an aryl or heteroaryl aldehyde with 1,3-acetonedicarboxylic acid.