US Patent 7514088 Multivalent Clostridial toxin derivatives and methods of their use
Patent 7514088 was granted and assigned to Allergan, Inc. on April, 2009 by the United States Patent and Trademark Office.
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The present invention is directed to multivalent Clostridial neurotoxin derivatives having more than one binding domain directed to a cell surface feature of a target cell. Such modified neurotoxins are useful as therapeutic compositions to prevent exocytosis and secretion by the target cell. Conditions in which such compositions man be useful include, without limitation, disorders of the sensory or motor nervous system, acute or chronic pain, cancer, pancreatitis, hyperhydrosis, glandular disorders, viral infections, cystic fibrosis and the like. The invention is also directed to methods of using and administering such a composition, and methods of treating a given condition using such a composition.
US Patent 07514088 Multivalent Clostridial toxin derivatives and methods of their use US Patent 7514088 Multivalent Clostridial toxin derivatives and methods of their use
US Patent 07514088 Multivalent Clostridial toxin derivatives and methods of their use
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