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US Patent 7524499 Modified chimeric polypeptides with improved pharmacokinetic properties

Patent 7524499 was granted and assigned to Regeneron Pharmaceuticals, Inc. on April, 2009 by the United States Patent and Trademark Office.

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US Patent 12103960 VEGF traps and mini-traps and methods for treating ocular disorders and cancer
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US Patent 12077570 Anti-VEGF protein compositions and methods for producing the same
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US Patent 12012444 Anti-VEGF protein compositions and methods for producing the same
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US Patent 12005097 Aflibercept formulations and uses thereof
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Patent abstract

Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal.

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US Patent 11753459 Anti-VEGF protein compositions and methods for producing the same
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=0752449900
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US Patent 07524499 Modified chimeric polypeptides with improved pharmacokinetic properties US Patent 7524499 Modified chimeric polypeptides with improved pharmacokinetic properties

Infobox
Patent Number
0752449900
Patent Number
752449900
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Infobox
Is a
Patent
Patent
0
Current Assignee
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
075244990
Date of Patent
April 28, 2009
0
Patent Application Number
121026480
Date Filed
April 14, 2008
0
Official Website
https://pdfpiw.uspto.gov/.piw?Docid=075244990
Patent Primary Examiner
‌
Christine J. Saoud
0
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edited on 26 Sep, 2022
Infobox
Is a
Patent
Patent
0
Current Assignee
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
075244990
Date of Patent
April 28, 2009
0
Patent Application Number
121026480
Date Filed
April 14, 2008
0
Official Website
https://pdfpiw.uspto.gov/.piw?Docid=075244990
Patent Primary Examiner
‌
Christine J. Saoud
0
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Website URL
https://pdfpiw.uspto.gov/.piw?Docid=07524499
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 US Patent 07524499 Modified chimeric polypeptides with improved pharmacokinetic properties

Infobox
Is a
Patent
Patent
Current assignee
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
07524499
Date of patent
April 28, 2009
Patent application number
12102648
Date Filed
April 14, 2008
Patent primary examiner
‌
Christine J. Saoud

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