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US Patent 7530940 Methods of enhancing radiation effects with metal nanoparticles

Patent 7530940 was granted and assigned to Nanoprobes on May, 2009 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Current Assignee
Nanoprobes
Nanoprobes
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7530940
Date of Patent
May 12, 2009
Patent Application Number
10705614
Date Filed
November 10, 2003
Patent Primary Examiner
‌
Charles A. Marmor, II
Patent abstract

The present invention provides methods of using metal nanoparticles 0.5 to 400 nm in diameter to enhance the dose and effectiveness of x-rays or of other kinds of radiation in therapeutic regimes of ablating a target tissue, such as tumor. The metal nanoparticles can be administered intravenously, intra-arterially, or locally to achieve specific loading in and around the target tissue. The metal nanoparticles can also be linked to chemical and/or biochemical moieties which bind specifically to the target tissue. The enhanced radiation methods can also be applied to ablate unwanted tissues or cells ex vivo.

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