Patent 7531343 was granted and assigned to GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. on May, 2009 by the United States Patent and Trademark Office.
The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing activity in microorganisms. In specific embodiments, the invention provides methods for inducing and stabilizing nitrile hydratase activity, amidase activity, and asparaginase I activity. The invention further provides compositions comprising enzymes or microorganisms having induced and/or stabilized activity.