Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 26, 2009
Patent Application Number
11273276
Date Filed
November 14, 2005
Patent Primary Examiner
Patent abstract
Provided is a method for preparing letrozole, which includes reacting an activated bis-(4-cyanophenyl)-methane with a triazole to produce letrozole, and, optionally, purifying the letrozole. Also provided are highly pure letrozole, and a method of purifying letrozole, which method includes precipitating letrozole, e.g., by selective precipitation from a reaction mixture and/or by subjecting the letrozole to one or more crystallizations.
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