Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Anita Van Kimmenade0
Eugenio Ferrari0
Date of Patent
June 9, 2009
0Patent Application Number
117258360
Date Filed
March 19, 2007
0Patent Primary Examiner
Patent abstract
The present invention relates to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms having exogenous nucleic acid sequences introduced therein and methods for producing proteins in such host cells, such as members of the genus Bacillus. More specifically, the present invention relates to the expression, production and secretion of a polypeptide of interest and to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention provides for the enhanced expression of a selected polypeptide by a microorganism.
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