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US Patent 7547551 Transfection of eukaryontic cells with linear polynucleotides by electroporation

Patent 7547551 was granted and assigned to University of Antwerp on June, 2009 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides an improved method for gene delivery in eukaryotic cells by electroporation, preferably in human hematopoietic cells, particular dendritic cells. The method of the invention is superior to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for gene delivery, including tumor antigen loading of dendritic cells.

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