Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
June 23, 2009
Patent Application Number
11264737
Date Filed
November 1, 2005
Patent Citations Received
Patent Primary Examiner
Patent abstract
An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.
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