Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Terry R. Magnuson0
Ellis D. Avner0
Richard P. Woychik0
Date of Patent
June 30, 2009
0Patent Application Number
109948100
Date Filed
November 22, 2004
0Patent Primary Examiner
Patent abstract
The present invention relates to methods of producing an allelic series of modifications in genes of interest in a cell. In particular, the invention provides methods for using nucleic acid sequence-modifying agents (e.g., chemicals, electromagnetic radiation, etc.) to introduce modifications in any nucleic acid sequence in the genome of a cell. Also provided are sets of cells which contain at least one modification in any gene of interest. The methods and compositions of the invention are useful in determining the function of the gene of interest.
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