Patent attributes
A method for determining metabolic flux distribution of a cell, which comprises the steps of:1) creating a stoichiometric matrix based on formulas of biochemical reactions from a substrate to a product,2) computing a set of vectors of solutions existing in a solution space which the stoichiometric matrix may have,3) selecting, from the computed set of vectors of solutions, maximum vectors whose vector elements corresponding to respective substances for which input values can be obtained are maximum, and4) performing linear combination for the selected vectors in accordance with the following equations to obtain a vector representing metabolic flux distribution: