Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kathleen D. Danenberg0
Date of Patent
July 14, 2009
0Patent Application Number
113415150
Date Filed
January 30, 2006
0Patent Primary Examiner
Patent abstract
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing TS and/or ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and prognosticate the probable resistance of a patient's tumor to treatment with 5-FU and oxaliplatin-based therapies by examination of the amount of TS and/or ERCC1 mRNA in a patient's tumor cells and comparing it to a predetermined threshold expression level for those genes. More specifically, the invention provides to oligonucleotide primer pairs ERCC1 and TS and methods comprising their use for detecting levels of ERCC1 and TS mRNA, respectively.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
