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US Patent 7563598 Detection of truncation mutations by mass spectrometry

Patent 7563598 was granted and assigned to Ambergen on July, 2009 by the United States Patent and Trademark Office.

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Current Assignee
Ambergen
Ambergen
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
75635980
Date of Patent
July 21, 2009
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Patent Application Number
114871280
Date Filed
July 14, 2006
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Patent Primary Examiner
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Deborah Crouch
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Patent abstract

This invention relates to the detection and analysis by mass spec of nascent proteins, and in particular truncated proteins, translated within cellular or cell-free translation systems. N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as a mass difference.

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