Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 18, 2009
Patent Application Number
11115877
Date Filed
April 27, 2005
Patent Primary Examiner
Patent abstract
Members of the TGF-β superfamily control many physiologic and pathophysiologic processes in multiple tissues and signal via type II and type I receptor serine kinases. Type II activin receptors are promiscuous and known to bind 12 TGF-β ligands including activins, myostatin, BMPs and nodal. Methods are described for the screening and identification of antagonist for TGF-β superfamily members, in particular activin-A antagonist.
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