Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
September 8, 2009
Patent Application Number
11438749
Date Filed
May 22, 2006
Patent Primary Examiner
Patent abstract
The present invention concerns the discovery of a new family of hedgehog binding proteins, referred to herein as “hedgehog interacting proteins” or “HIPs”, which are demonstrated to bind to hedgehog polypeptides with high affinity. As described herein, the vertebrate HIP proteins exhibit spatially and temporally restricted expression domains indicative of important roles in hedgehog-mediated induction.
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