Patent 7589070 was granted and assigned to The Children'S Hospital Of Philadelphia on September, 2009 by the United States Patent and Trademark Office.
A therapeutic delivery system efficiently introduces biologically active molecules to mammalian cells without the use of synthetic polymers or biopolymer coatings. Surface modification of a metal support, such as a medical device, results in a single molecular layer that can fasten various molecules, thereby minimizing any cellular inflammatory response while enhancing biocompatibility.