Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Virginie Louvain0
Elsa Bianchini0
Martine Aiach0
Pierre-Emmanuel Marque0
Bernard Le Bonniec0
Claire Calmel0
Date of Patent
September 15, 2009
0Patent Application Number
104921910
Date Filed
October 18, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to chimeric proteins comprising an artificial sequence for cleavage by thrombin, in which the activation peptide is fibrinopeptide A. Preferably, said chimeric proteins are derived from the zymogen of a serine protease such as PC or FX, by replacing the activation peptide of said zymogen with fibrinopeptide A, or a portion thereof, comprising at least amino acids P10 to P1 of said fibrinopeptide.
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