Patent 7591994 was granted and assigned to IMMUNOMEDICS, INC. on September, 2009 by the United States Patent and Trademark Office.
The invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a camptothecin as a therapeutic moiety, and further relates to processes for making and using the said conjugates.