Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Arnout F. Gerritsen0
Edward Halk0
Jan G. J. van de Winkel0
Jørgen Petersen0
Marcus A. van Dijk0
Ole Baadsgaard0
Date of Patent
September 29, 2009
0Patent Application Number
103200940
Date Filed
December 16, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Isolated human monoclonal antibodies which specifically bind to human EGFR, and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced by a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
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