Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
J. Carl Barrett0
Izumi Horikawa0
Date of Patent
October 6, 2009
0Patent Application Number
104568300
Date Filed
June 5, 2003
0Patent Primary Examiner
Patent abstract
Artificial TERT promoters, which are useful for enhancing the differential expression of operably linked heterologous nucleic acid sequences, such as polypeptide cytotoxins, are disclosed herein. Methods for treating disease cells, such as cancer cells, while minimizing effects on normal, somatic cells by administering therapeutically effective amounts of heterologous nucleic acid sequences operably linked to artificial TERT promoters are provided. Kits containing artificial TERT promoters for enhancing differential expression are also provided.
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