Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Darren J. Carrozzella0
Guojie Ho0
Date of Patent
October 6, 2009
0Patent Application Number
115003780
Date Filed
August 8, 2006
0Patent Primary Examiner
Patent abstract
This invention provides a method for making maytansinoids having a chiral amino acid side chain, such as DM1 and DM4 that are used to treat cancer. According to this method, the side chain may be added with little epimerization of the amino acid chiral center.
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