Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Xiaojing Yang0
Tao Wang0
Tiruvettipuram K. Thiruvengadam0
Vijay Sabesan0
Anantha R. Sudhakar0
Daw-long Kwok0
Frank Xing Chen0
George Wu0
...
Date of Patent
October 20, 2009
0Patent Application Number
113313240
Date Filed
January 12, 2006
0Patent Primary Examiner
Patent abstract
This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by the following:
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