Patent 7608678 was granted and assigned to Nektar (pulminary therapeutics business unit) on October, 2009 by the United States Patent and Trademark Office.
A water soluble polymer is described, the water soluble polymer comprising multiple hydrolytically degradable carbonate linkages in a backbone and, for each carbonate linkage in the backbone, an oligomer linked thereto by the carbonate linkage, wherein the oligomer is branched and, prior to being linked by the carbonate linkage, has the formula:R3[O—(—CHR1CH2—O—)n—]mHwhere R3 is a core branching moiety, R1 is H, (n) can range from 2 to 2000, and m is at least 3.