Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zhiyong Shen0
Hao Yan0
Nadrian Seeman0
Xiaoping Zhang0
Date of Patent
November 3, 2009
0Patent Application Number
103701010
Date Filed
February 21, 2003
0Patent Primary Examiner
Patent abstract
The present invention is directed to a sequence dependent polynucleotide nanomechanical device based on a nucleic acid paranemic crossover (PX) molecule which is a four-stranded structure related to parallel double crossover molecules, except that every possible crossover takes place. Eliminating two crossovers leads to a topoisomer, termed JX2, in which one pair of ends are switched (rotated 180°) while the other pair of ends remain the same. The device can be cycled between the two states, PX and JX2, by replacing single strands that set the state to be PX or JX2.
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