A seal assembly for mobile living quarters seals around a slide-out room, includes a pair of attaching members extending along the inside and outside surfaces of the main living area wall at an aperture through which the slide-out room moves, and further includes a connecting member extending between the attaching members and along the edge of the wall defining the aperture. A wiper seal extends from the connecting member to flex against the walls of the slide-out room, and the connecting member further includes an accordion pleat for adjusting the distance between the attaching members to thereby accommodate walls of different thicknesses.