US Patent 7615615 Modified interferon beta with reduced immunogenicity
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Patent Inventor Names
Francis J. Carr0
Graham Carter0
John Watkins0
Matthew Baker0
Tim Jones0
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Patent abstract
The present invention relates a modified human interferon beta (INFβ) which is less immunogenic than human INFβ (SEQ ID NO: 1) when administered in vivo to a human. The modified human INFβ comprises an amino acid residue sequence that differs from SEQ ID NO: 1 by an amino acid residue substitution selected from the group consisting of L57A, L57C, L57D L57E, L57G, L57H, L57K, L57N, L57P, L57Q, L57R, L57S, and L57T and an additional substitution selected from the group consisting of the H140A, H140C, H140G, and H140P.
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US Patent 07615615 Modified interferon beta with reduced immunogenicity US Patent 7615615 Modified interferon beta with reduced immunogenicity
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Patent Number
076156150
Patent Number
76156150
Edits on 31 Mar, 2023
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Patent Jurisdiction
Patent Number
076156150
Date of Patent
November 10, 2009
0Patent Application Number
120771200
Date Filed
March 17, 2008
0Official Website
Patent Primary Examiner
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US Patent 07615615 Modified interferon beta with reduced immunogenicity
Infobox
Is a
Patent jurisdiction
Patent number
07615615
Date of patent
November 10, 2009
Patent application number
12077120
Date Filed
March 17, 2008
Patent primary examiner
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