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US Patent 7623910 ECG-based differentiation of LQT1 and LQT2 mutation

Patent 7623910 was granted and assigned to University of Rochester on November, 2009 by the United States Patent and Trademark Office.

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Current Assignee
University of Rochester
University of Rochester
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7623910
Date of Patent
November 24, 2009
Patent Application Number
11685016
Date Filed
March 12, 2007
Patent Citations Received
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US Patent 12123882 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
0
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US Patent 11754566 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
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US Patent 12019080 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
0
Patent Primary Examiner
‌
Mark W. Bockelman
Patent abstract

A method differentiating LQT1 mutation from LQT2 mutation is disclosed. An ECG signal is obtained for a patient. At least a first ECG parameter and a second ECG parameter are determined from the ECG signal. A probability that the patient is an LQT1 carrier or an LQT2 carrier is determined based on a regression model which takes into account the first ECG parameter and the second ECG parameter. A system for assessing repolarization abnormalities is also disclosed. The system has a processor configured to differentiate between LQT1 and LQT2 based on at least two ECG parameters from ECG data. The system also has a data input coupled to the processor and configured to provide the processor with the ECG data. The system further has a user interface coupled to either the processor or the data input.

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