Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
K. Dane Wittrup0
Richard J. H. Begent0
Christilyn P. Graff0
Kerry Ann Chester0
Date of Patent
December 1, 2009
0Patent Application Number
118029890
Date Filed
May 29, 2007
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to improved antibodies against tumor surface antigens and their use in the treatment of tumors. Of particular interest are highly stable, humanized, high affinity antibodies against carcinoembryonic antigen (CEA), especially the antibody we have termed sm3E, which is derived from the scFv antibody MFE-23. Such antibodies have the potential for improved therapeutic efficacy.
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