Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Matthew During0
Michael Kaplitt0
Date of Patent
January 12, 2010
0Patent Application Number
108024170
Date Filed
March 16, 2004
0Patent Primary Examiner
Patent abstract
The invention provide methods and compositions for localized delivery of a vector comprising a therapeutic agent to a specific region of the brain that is overstimulated in neurodegenerative diseases. In particular, the invention provides methods and compositions used to deliver an adeno-associated virus vector (AAV) comprising a nucleotide sequence encoding glutamic acid decarboxylase (GAD) to cells in the subthalmic nucleus of the basal ganglia, mesaphilia and thalamus.
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